Abstract: In this paper, research was carried out on the coupling relationship between the spontaneous combustion and gas explosion in the gob from the microscopic mechanism level according to the stage characteristics of the temperature rise process caused by the residual coal spontaneous combustion in the gob, by taking the constant-volume reactor as the model and by using the numerical simulation software CHEMKIN to simulate the change of the reaction time, pressure and intermediate product before and after the gas explosion at three stages of slow oxidation, accelerating oxidation and violent oxidation. The numerical calculation results showed that the gas explosion was inhibited at the slow oxidation stage; the gas explosion was promoted at the accelerating oxidation stage; and the gas explosion was slightly promoted at the violent oxidation stage.