Abstract: In order to accurately predict the stability movement trend of the healthy development system of Kuangou Coal Mine, 20 factors affecting the stability of the system were analyzed comprehensively and divided into 5 subsystems. The simulation model (SD model) was established by using the principle of system dynamics and Vensim software. Firstly, the interaction relationship between each influence factor and its feedback relationship with the subsystem were analyzed, and the causal loop diagram and the stock flow diagram were drawn; secondly, the influence factors and the weight of subsystems were analyzed by priority map method (PC), and the parameters of SD model were determined based on the security level evaluation criteria and expert scores; finally, Vensim software was used to simulate and predict impact factors and subsystems under different input schemes, and the main influence factor of each subsystem, as well as the key subsystem that determined the stability of the healthy development system of coal mine were obtained, and the optimal input scheme was determined. The analysis results show that in order to improve the stability of the mine health development system, Kuangou Coal Mine needs to increase the investment in four aspects:system management capabilities, investment in advanced equipment, introduction of scientific and technological talents and safety education and training, and focus on scientific research investment.