Abstract: Taking Wenjiapo Coal Mine in Binchang Mining Area as the engineering background, on the basis of mastering the hydrogeology and mining conditions of the research area, the "big well method" based on two different geological models, as well as "vertical infiltration lateral runoff method" and "water collection gallery method" and other different analytical methods were adopted, the water inflow in 4101 working face in Wenjiapo Coal Mine was predicted. The calculated results of water inflow obtained by different methods were compared with the measured water inflow in working face. It is concluded that the calculated results of "vertical infiltration lateral runoff" method are more consistent with the measured values, which can reflect the characteristics of water inflow more accurately. The application of this method provides an important reference for the calculation of water inflow under similar hydrogeological conditions.