Abstract: In order to solve the problem that coal dust is not easily wetted by water, surfactant is selected to be compounded and added into water to make a compound solution, so as to improve the wettability of water to coal dust. Five kinds of surfactants were selected through the experiments of coal dust sedimentation with twenty-two different types of surfactants, and nine kinds of surfactant compounding solutions were obtained by the equal dose compounding of the optimal surfactants, the experiment of coal dust sedimentation was carried out on the surfactant compound solution again. The experimental results show that, when the mass fraction of the mixture is from 0.20% to 0.60%, the compound solution of Rapid Panetrant T and SAS-60 has better wetting effect on coal dust than SAS-60 solution; when the mass fraction of the mixture is from 0.30% to 0.50%, the compound solution of OA-12 and Lutensol XP-90 has better wetting effect on coal dust than that of two single surfactant solution.