Abstract: According to the data of air resistance and air quantity provided by Guangning Yanghui coal mine, based on the theory about the sensitivity of air quantity and self-developed software which used to identify fluid network angular branch and analysis system sensitivity, the sensitivity of the ventilation system, as well as the influence and reaction of each branch were obtained. The stability of ventilation system in Guangning Yanghui coal mine was analyzed. It also provided the theoretical basis for the future improvement of ventilation system, roadway maintenance and construction.