Abstract: Separation grouting is an important technology to achieve surface subsidence reduction and green mining,and the injection of slurry into the separation space will also affect the characteristic of mine pressure behavior in the working face. Taking the 2309 working face of Zhaozhuang No. 2 well as the engineering background, the mine pressure behavior under different mining stages was compared and analyzed. The results show that:the average end resistance of the whole face is 2 601. 6 kN and pressure step is 24. 2 m in the normal mining stage,and the average end resistance of the whole face is 3 229. 1 kN and pressure step is 16. 5 m in the mining stage with separation grouting,compared with the normal mining,the end resistance of the support in the case of separation grouting is obviously increased,and the periodic pressure step is reduced;When the working face is drilled through grouting borehole,the working resistance of the support increases as a whole in the direction of the trend, and incline to gradually decrease from the middle to the two sides;Under the combined action of the grout support reaction force, self-weight and grouting pressure,the underlying rock layer is compacted and the force of the rock beam is increased,which leads to the increase of end resistance of the support and the decrease of the periodic pressure step,the morphology of separation space and the arrangement of the grouting borehole lead to a higher stress on the inclined middle support. The proposed inducements explain the special characteristic of mining pressure behavior in the separation grouting working face.