Abstract: In order to realize the purpose of accurate, time-saving and reliable connection of rescue wells, the trajectory design method involved in the application of emergency rescue drilling site technology was analyzed. According to different trajectory design objectives and constraint requirements, the types and methods of trajectory design for rescue wells under different working conditions were summarized. Then, the design of the connecting trajectory of the rescue well was studied based on practical example, and a set of trajectory connecting method which was efficient and suitable for mine emergency rescue drilling was explored. Finally, starting from the application of the software of rescue well trajectory optimization, combined with the correction operation practice of mine rescue well, the applicability and existing shortcomings of the drilling software in the rescue field were analyzed, and the corresponding suggestions for improvement were put forward. The research results can provide reference and guidance for emergency rescue of mine, oil and gas well, underground space and other disasters.