Abstract: Monotonous monitoring and scheduling operations in intelligent mines are prone to cause cognitive fatigue among operators, thereby reducing work performance and affecting coal mine safety production. This study expounded three main cognitive processes involved in monitoring and scheduling tasks, including information perception, information processing and information output. Cognitive task analysis methods such as formal model, process tracking and unstructured interview were used to analyze it. This study used human physiological parameters, subjective rating parameters and task performance parameters of the subjects to assess cognitive fatigue through experiments. The SPSS 22.0 statistical software was used to explore the changes in the degree of cognitive fatigue of the subjects in different time periods. Through computer simulation of intelligent mine monitoring and scheduling operations, the dual task operation mode successfully induced cognitive fatigue of the subjects. The KSS and SPC scales and task performance indicators show that fatigue and lethargy will increase and work performance will decrease during the long time monotonous monitoring of intelligent mine operators. Reaction time and subjective scale parameters can reflect the change of cognitive fatigue state of the subjects, but the characterization effect of heart rate parameter is not obvious.