Abstract: To improve the situation of coal mine safety investment structure to better serve coal mine safety production, the interrelationship of factors influencing coal mine safety investment structure was studied. By analyzing the safety structure of coal mine enterprises through m-IHEL theory, the coal mine safety system was divided into four sub-systems, including human, machine, environment and information. The evaluation index system of coal mine safety investment structure was constructed. The AHP-DEMATEL-ISM model was used for analysis and evaluation. The results show that safety education and training, mining safety equipment, information management system and safety monitoring system are the key factors affecting the safety investment structure of coal mines. The enterprises should increase the investment of personnel, pay attention to the role of environment and information in the coal mine system, and improve the intelligence management level of coal mines.