Abstract: Most of the existing positioning terminals only have the functions of accurate positioning, evacuation alarm, emergency SOS, etc., but can not realize the vital signs monitoring function. In order to solve the problem, a positioning watch with health monitoring based on UWB technology was designed. The watch adopts the TOF positioning algorithm so as to realize the accurate positioning of mine roadway, transmits accurate positioning data and vital signs health data of underground personnel to the server, and realizes real-time monitoring of personnel location information and health data. The key technologies of positioning watch with health monitoring mainly include: linear TOF positioning algorithm of mine roadway, vital signs monitoring technology such as heart rate, blood oxygen and body temperature, three-axis sensor to detect motion state and low-power hibernation mechanism. The test results show that the positioning accuracy of the watch is ≤±0.30 meters, the positioning distance can be up to 400 meters, the monitoring function of vital signs such as heart rate, blood oxygen and body temperature is normal, the average working current is less than 2 mA, and the minimum resting current is less than 500 μA. It meets the intelligent and diversified needs of positioning terminals.