Abstract: In order to improve the sensitivity analysis efficiency of complex fluid networks, the method of fluid network sensitivity matrix module integration was proposed based on the equivalent simplification theory of fluid network, and the integration calculation formula of fluid network module branch sensitivity was derived.The integrated calculation of the sensitivity input, output and branches in the equivalent simplified module of fluid network was realized. An example was used to illustrate the implementation process of sensitivity integration calculation and analyze the law of sensitivity integration process and influence factor. The proposed sensitivity integrated calculation method realizes the equivalent simplification of the sensitivity matrix of complex fluid network, and improves the stability analysis efficiency of complex fluid network.